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These domains form a ligand-binding pocket within the cell membrane, enabling the transmission of extracellular signals to trigger intracellular responses [13]

Next, we detected the GPX4 and FTH1 levels in colorectal cancer patients undergoing neoadjuvant chemoradiotherapy by immunohistochemistry, and found both protein levels were up-regulated, compared with the patients without neoadjuvant chemoradiotherapy ( Figure 6A )

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